ICIP 2006, Atlanta, GA
 

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Paper Detail

Paper:MP-P4.10
Session:Biomedical Image Reconstruction
Time:Monday, October 9, 14:20 - 17:00
Presentation: Poster
Topic: Biomedical Imaging: Molecular and cellular bioimaging
Title: 3-D RECONSTRUCTIONS OF TAILED BACTERIOPHAGES FROM CYRO ELECTRON MICROSCOPY IMAGES
Authors: Cory J. Prust; Purdue University 
 Peter C. Doerschuk; Purdue University 
 John E. Johnson; Scripps Research Institute 
Abstract: A 3-D reconstruction problem for virus particles based on cryo electron microscope images is described in which a spatially localized deviation from total-particle symmetry is present. In particular, we describe a statistical algorithm for the reconstruction of tailed bacteriophages where the symmetries of the capsid and tail are incompatible and therefore the tail is a deviation from symmetry. For reasons of computational complexity and reduced storage, we propose a two-step approach to reconstruction. Mathematical models and numerical results computed from synthetic data are presented.