 |
Technical Program
Paper Detail
| Paper: | MP-P4.10 |
| Session: | Biomedical Image Reconstruction |
| Time: | Monday, October 9, 14:20 - 17:00 |
| Presentation: |
Poster
|
| Title: |
3-D RECONSTRUCTIONS OF TAILED BACTERIOPHAGES FROM CYRO ELECTRON MICROSCOPY IMAGES |
| Authors: |
Cory J. Prust; Purdue University | | | | | Peter C. Doerschuk; Purdue University | | | | | John E. Johnson; Scripps Research Institute | | |
| Abstract: |
A 3-D reconstruction problem for virus particles based on cryo electron microscope images is described in which a spatially localized deviation from total-particle symmetry is present. In particular, we describe a statistical algorithm for the reconstruction of tailed bacteriophages where the symmetries of the capsid and tail are incompatible and therefore the tail is a deviation from symmetry. For reasons of computational complexity and reduced storage, we propose a two-step approach to reconstruction. Mathematical models and numerical results computed from synthetic data are presented. |
|
